Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15954401 | 0.90 | MAOB (0.47) | MAOBFAAHCCR3 | |
| SCHEMBL3867303 | 0.83 | KDM4E (0.44) | OPRK1KDM4EALDH1A1SLC18A3HDAC6 | |
| SCHEMBL9051255 | 0.82 | SLC18A3 (0.58) | OPRK1KDM4EALDH1A1SLC18A3HDAC6 | |
| SCHEMBL1575563 | 0.82 | GPR119 (0.54) | KDM4EALDH1A1FAAH | |
| SCHEMBL1582103 | 0.82 | FAAH (0.52) | MAOBOPRK1SLC18A3HDAC6KDM1A | |
| SCHEMBL28772160 | 0.82 | GPR119 (0.54) | — | |
| SCHEMBL27953755 | 0.81 | MEN1 (0.54) | FAAHCCR3 | |
| SCHEMBL10296248 | 0.80 | FAAH (0.42) | MAOBOPRK1SPHK1KDM4EALDH1A1 | |
| SCHEMBL1581904 | 0.80 | MAOB (0.49) | MAOBOPRK1SLC18A3HDAC6HDAC1 | |
| SCHEMBL26641460 | 0.79 | CPB1 (0.46) | OPRK1KDM4EALDH1A1SLC18A3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910290-A2 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003962-A2 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |