SCHEMBL10299934

SCHEMBL10299934

CC=C(CCCCC)c1ccc2c(c1)Oc1cc(C)ccc1N2c1ccc(CCCC)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.34
MGLL Q99685 1/20 0.34
PLK1 P53350 7/20 0.34
PLK3 Q9H4B4 2/20 0.34
THRA P10827 7/20 0.33
THRB P10828 7/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2B6 P20813 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2607155 0.84 MGLL (0.42) FAAHMGLLPLK1NPC1TP53
SCHEMBL19320303 0.82 FAAH (0.50) FAAHMGLLPLK1NPC1TP53
SCHEMBL10299933 0.81 FAAH (0.36) FAAHMGLLPLK1NPC1TP53
SCHEMBL11916914 0.80 MGLL (0.39) FAAHMGLLNPC1TP53POLB
SCHEMBL12108002 0.79 P2RX4 (0.38) FAAHMGLLNPC1TP53POLB
SCHEMBL13429568 0.78 NPC1 (0.38) FAAHMGLLNPC1TP53POLB
SCHEMBL13429571 0.75 FAAH (0.43) FAAHMGLLPLK1NPC1TP53
SCHEMBL11976635 0.75 RAB9A (0.40) FAAHMGLLNPC1RAB9ASMN1; SMN2
SCHEMBL18083583 0.74 HSD11B1 (0.37) FAAHMGLLNPC1TP53POLB
SCHEMBL19996768 0.74 CNR2 (0.43) FAAHMGLLNPC1TP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217387-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-10 US disclosed
US-20100001263-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-07 US disclosed