SCHEMBL10301529

SCHEMBL10301529

CNCCCCC(C(=O)O)N(CC(=O)O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.38
KDM4A O75164 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
KISS1R Q969F8 1/20 0.34
FOLH1 Q04609 5/20 0.33
HTR2A P28223 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22797036 0.89 KDM4C (0.37) CPB2KDM4AKDM4CKISS1RFOLH1
SCHEMBL10301889 0.88 CPB2 (0.34) CPB2KDM4AKDM4CFOLH1
SCHEMBL14684122 0.87 KDM4A (0.31) KDM4AKDM4CKISS1RHTR2AHRH1
SCHEMBL12650478 0.86 TDP1 (0.41) CPB2KDM4AKDM4CKISS1RFOLH1
SCHEMBL13914133 0.83 FOLH1 (0.49) FOLH1
SCHEMBL20068327 0.83 FOLH1 (0.43) FOLH1
SCHEMBL8432965 0.81 TDP1 (0.35) KDM4AKDM4CFOLH1
SCHEMBL15215665 0.81 EPHX1 (0.45) FOLH1
SCHEMBL14366075 0.80 GPR84 (0.47)
SCHEMBL97745 0.80 CPB2 (0.41) CPB2KDM4AKDM4CKISS1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3277845-B1 BEADS FOR NUCLEIC ACID SEQUENCING GENAPSYS INC (US) 2021-07-07 EP disclosed
US-10925970-B2 Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein AFFYCON APS (DK) 2021-02-23 US disclosed
US-20200390104-A1 ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-12-17 US disclosed
US-10815248-B2 Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof SUN YI (US) 2020-10-27 US disclosed
US-9951085-B2 Labeled chemically reactive and biologically active comjugates, and methods and compositions thereof SUN YI (US) 2018-04-24 US disclosed
US-9951085-B2 Labeled chemically reactive and biologically active comjugates, and methods and compositions thereof SUN YI (US) 2018-04-24 US disclosed
US-20170354743-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN AFFYCON APS (DK) 2017-12-14 US disclosed
US-20170354743-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN AFFYCON APS (DK) 2017-12-14 US disclosed
WO-2016005474-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN AFFYCON APS (DK) 2016-01-14 WO disclosed
US-20150361090-A1 NOVEL LABELED CHEMICALLY REACTIVE AND BIOLOGICALLY ACTIVE COMJUGATES, AND METHODS AND COMPOSITIONS THEREOF SUN YI (US) 2015-12-17 US disclosed
US-9156772-B2 Fluoride-releasing compositions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-10-13 US disclosed
US-9156772-B2 Fluoride-releasing compositions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-10-13 US disclosed
US-20140088308-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2014-03-27 US disclosed
US-20140088308-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2014-03-27 US disclosed
US-20120264939-A1 Fluoride-Releasing Compositions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-10-18 US disclosed
US-20120264939-A1 Fluoride-Releasing Compositions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-10-18 US disclosed
US-8217173-B2 Fluoride-releasing compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2012-07-10 US disclosed
US-20100261902-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) 2010-10-14 US disclosed
US-7247384-B2 tip coated with a monolayer of ethylene glycol derivatives resists the adsorption of proteins THE UNIVERSITY OF HOUSTON (US) 2007-07-24 US disclosed
US-7247384-B2 tip coated with a monolayer of ethylene glycol derivatives resists the adsorption of proteins THE UNIVERSITY OF HOUSTON (US) 2007-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088308-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD CPB2 1518/4885KDM4A 3236/4885KDM4C 2763/4885
US-20150361090-A1 NOVEL LABELED CHEMICALLY REACTIVE AND BIOLOGICALLY ACTIVE COMJUGATES, AND METHODS AND COMPOSITIONS THEREOF CD44, GUSB, PAICS CPB2 1114/4885KDM4A 3265/4885KDM4C 2541/4885
US-10925970-B2 Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein CD2BP2, CACYBP, CALCOCO2 CPB2 641/4885KDM4A 3187/4885KDM4C 2263/4885
US-20120264939-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD CPB2 1518/4885KDM4A 3236/4885KDM4C 2763/4885
US-20100261902-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD CPB2 1518/4885KDM4A 3236/4885KDM4C 2763/4885
US-20200390104-A1 ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS GSDMD, GLMN, GDA CPB2 3886/4885KDM4A 2312/4885KDM4C 2159/4885
US-10815248-B2 Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof GUSB, PAICS, CD44 CPB2 1068/4885KDM4A 2917/4885KDM4C 2477/4885
US-20170354743-A1 SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN CD2BP2, CACYBP, CALCOCO2 CPB2 641/4885KDM4A 3187/4885KDM4C 2263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.