SCHEMBL10307315

SCHEMBL10307315

CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)C1O

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MAPT P10636 1/20 0.54
▸ LGALS8 O00214 2/20 0.54
▸ GAA P10253 2/20 0.50
▸ TYR P14679 1/20 0.50
▸ ACHE P22303 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ G6PD P11413 1/20 0.49
▸ PYGB P11216 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13576889 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL14421703 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL136446 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL166332 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL14898436 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL12304019 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL50473 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL12632768 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL21847893 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL20745165 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9962344-B2 Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS, INC. (US) 2018-05-08 — — US disclosed
US-20170020829-A1 Chemosensory Receptor Ligand-Based Therapies ANJI PHARMACEUTICALS INC. 2017-01-26 — — US disclosed
US-9463170-B2 Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS, INC. (US) 2016-10-11 — — US disclosed
US-20150265555-A1 Chemosensory Receptor Ligand-Based Therapies ANJI PHARMACEUTICALS INC. 2015-09-24 — — US disclosed
US-9050292-B2 Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS, INC. (US) 2015-06-09 — — US disclosed
US-20140030332-A1 Chemosensory Receptor Ligand-Based Therapies ELCELYX THERAPEUTICS, INC. (US) 2014-01-30 — — US disclosed
US-20120177730-A1 Chemosensory Receptor Ligand-Based Therapies ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120177730-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 L3MBTL1 2860/4885MAPT 3632/4885LGALS8 627/4885
US-20150265555-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 L3MBTL1 2860/4885MAPT 3632/4885LGALS8 627/4885
US-20170020829-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 L3MBTL1 2860/4885MAPT 3632/4885LGALS8 627/4885
US-20140030332-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 L3MBTL1 2860/4885MAPT 3632/4885LGALS8 627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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