SCHEMBL12632768

SCHEMBL12632768

CO[C@H]1OC(CO)[C@H](O)[C@H](O)C1O

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ MAPT P10636 1/20 0.54
▸ LGALS8 O00214 2/20 0.54
▸ GAA P10253 2/20 0.50
▸ TYR P14679 1/20 0.50
▸ ACHE P22303 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ G6PD P11413 1/20 0.49
▸ PYGB P11216 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13576889 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL14421703 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL136446 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL166332 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL14898436 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL12304019 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL50473 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL21847893 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL20745165 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR
SCHEMBL10307315 1.00 L3MBTL1 (0.56) L3MBTL1MAPTLGALS8GAATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS UNIV YALE (US) 2024-02-29 — — US disclosed
EP-3434684-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION Keio University (JP) 2019-01-30 — — EP disclosed
US-20180111955-A1 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-26 — — US disclosed
US-9856283-B2 Thiosaccharide mucolytic agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-02 — — US disclosed
WO-2017163808-A1 COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION 学校法人慶應義塾 2017-09-28 — — WO disclosed
US-9717790-B2 Sphingoglycolipid analogues VICTORIA LINK LIMITED (NZ) 2017-08-01 — — US disclosed
US-9717790-B2 Sphingoglycolipid analogues VICTORIA LINK LIMITED (NZ) 2017-08-01 — — US disclosed
US-9586985-B2 Organic compounds as proantigens for natural killer T cells VICTORIA LINK LIMITED (NZ) 2017-03-07 — — US disclosed
US-20160136267-A1 SPHINGOGLYCOLIPID ANALOGUES VICTORIA LINK LIMITED (NZ) 2016-05-19 — — US disclosed
US-20160136267-A1 SPHINGOGLYCOLIPID ANALOGUES VICTORIA LINK LIMITED (NZ) 2016-05-19 — — US disclosed
US-20160060284-A1 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-03-03 — — US disclosed
US-20160060284-A1 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-03-03 — — US disclosed
US-20150191503-A1 ORGANIC COMPOUNDS VICTORIA LINK LIMITED (NZ) 2015-07-09 — — US disclosed
WO-2014200363-A1 SPHINGOGLYCOLIPID ANALOGUES VICTORIA LINK LIMITED (NZ) 2014-12-18 — — WO disclosed
WO-2014153009-A2 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) 2014-09-25 — — WO disclosed
US-8551959-B2 Glycolipid and use thereof RIKEN (JP) 2013-10-08 — — US disclosed
US-8551959-B2 Glycolipid and use thereof RIKEN (JP) 2013-10-08 — — US disclosed
US-8299223-B2 Pseudoglycolipid and use thereof RIKEN (JP) 2012-10-30 — — US disclosed
US-20110104188-A1 NOVEL GLYCOLIPID AND USE THEREOF RIKEN (JP) 2011-05-05 — — US disclosed
US-20100062990-A1 NOVEL PSEUDOGLYCOLIPID AND USE THEREOF RIKEN (JP) 2010-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110104188-A1 NOVEL GLYCOLIPID AND USE THEREOF SGMS1, UGCG, SGPL1 L3MBTL1 2364/4885MAPT 4438/4885LGALS8 108/4885
US-20180111955-A1 THIOSACCHARIDE MUCOLYTIC AGENTS MUC1, TREH, FUT6 L3MBTL1 3570/4885MAPT 4252/4885LGALS8 109/4885
US-20160136267-A1 SPHINGOGLYCOLIPID ANALOGUES UGCG, SGPL1, SMPD2 L3MBTL1 609/4885MAPT 3433/4885LGALS8 156/4885
US-20160060284-A1 THIOSACCHARIDE MUCOLYTIC AGENTS MUC1, TREH, FUT6 L3MBTL1 3570/4885MAPT 4252/4885LGALS8 109/4885
US-20150191503-A1 ORGANIC COMPOUNDS SGMS1, UGCG, SGMS2 L3MBTL1 894/4885MAPT 1967/4885LGALS8 185/4885
US-20240067756-A1 CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS BRDT, PAICS, KLK3 L3MBTL1 860/4885MAPT 199/4885LGALS8 2516/4885
US-20100062990-A1 NOVEL PSEUDOGLYCOLIPID AND USE THEREOF PNLIP, SGMS1, SGPL1 L3MBTL1 879/4885MAPT 4600/4885LGALS8 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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