SCHEMBL10312353

SCHEMBL10312353

CS(=O)(=O)N(CCC[Si](CO)(CO)CO)c1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PER2 O15055 2/20 0.47
CRY1 Q16526 2/20 0.47
CRY2 Q49AN0 2/20 0.47
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
NR1I2 O75469 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
MCL1 Q07820 3/20 0.35
BCL2L1 Q07817 2/20 0.35
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10312352 0.83 ESR1 (0.43) PER2CRY1CRY2SMN1; SMN2MEN1
SCHEMBL8899900 0.70 L3MBTL1 (0.61) PER2CRY1CRY2HTTNPSR1
SCHEMBL10312364 0.70 NR1I2 (0.56) L3MBTL1NR1I2LMNA
SCHEMBL10312354 0.67 ALDH1A1 (0.64) SMN1; SMN2GAAALDH1A1LMNA
SCHEMBL15702432 0.65 HTT (0.41) PER2CRY1CRY2HTTNPSR1
SCHEMBL11123788 0.64 L3MBTL1 (0.46) PER2CRY1CRY2HTTNPSR1
SCHEMBL15380457 0.64 PER2 (1.00) PER2CRY1CRY2HTTNPSR1
SCHEMBL4924525 0.62 L3MBTL1 (0.59) PER2CRY1CRY2HTTNPSR1
SCHEMBL14820 0.62 ESR1 (0.60) PER2CRY1CRY2L3MBTL1SMN1; SMN2
SCHEMBL16466748 0.62 APP (0.49) HTTNPSR1L3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828879-B2 Silicon-containing composition having sulfonamide group for forming resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-09 US disclosed
US-20120178261-A1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178261-A1 SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM STS, SI, MUS81 PER2 3381/4885CRY1 3699/4885CRY2 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.