Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003749 | 0.86 | NOD1 (0.43) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL10003760 | 0.84 | NOD2 (0.66) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL10003293 | 0.82 | NOD1 (0.43) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL10004659 | 0.80 | NOD2 (0.66) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL18332162 | 0.79 | NOD1 (0.51) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL12908806 | 0.79 | NOD2 (0.51) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL12908808 | 0.78 | PPARG (0.48) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL12908515 | 0.76 | NOD1 (0.50) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL10003582 | 0.76 | ALOX5 (0.39) | NOD1NOD2ALOX5PTGDR2LMNA | |
| SCHEMBL10003580 | 0.76 | ALOX5 (0.39) | NOD1NOD2ALOX5PTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471786-A1 | AMINOPYRAZOLE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011016528-A1 | AMINOPYRAZOLE DERIVATIVE | 中外製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |