Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARD | Q03181 | 8/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003459 | 0.86 | PPARG (0.46) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL12908515 | 0.84 | NOD1 (0.50) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL12908486 | 0.84 | ALOX5 (0.47) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL10313746 | 0.78 | NOD1 (0.45) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL12908806 | 0.76 | NOD2 (0.51) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL10313757 | 0.76 | ALOX5 (0.41) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL10003969 | 0.76 | ALOX5 (0.41) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL10003974 | 0.76 | ALOX5 (0.41) | PPARGPPARAPPARDNOD1NOD2 | |
| SCHEMBL29597969 | 0.74 | PPARG (0.51) | PPARGPPARAPPARDNOD1ALDH1A1 | |
| SCHEMBL28525103 | 0.74 | PPARG (0.51) | PPARGPPARAPPARDNOD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016528-A1 | AMINOPYRAZOLE DERIVATIVE | 中外製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |