Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002994 | 0.87 | NOD1 (0.48) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL12908808 | 0.84 | PPARG (0.48) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL10005014 | 0.79 | NOD1 (0.48) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL16015319 | 0.77 | NOD1 (0.41) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL10003073 | 0.77 | NOD1 (0.41) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL10003075 | 0.77 | NOD1 (0.41) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL28016375 | 0.76 | ACLY (0.47) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL10313746 | 0.76 | NOD1 (0.45) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL12908806 | 0.74 | NOD2 (0.51) | NOD1NOD2PPARGPPARDPPARA | |
| SCHEMBL13802524 | 0.73 | PPARG (0.52) | NOD1NOD2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016528-A1 | AMINOPYRAZOLE DERIVATIVE | 中外製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |