Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16396701 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAGFERTRPA1MAPT | |
| SCHEMBL394899 | 0.80 | NOS3 (0.45) | ALDH1A1GAANPC1RAB9ATRPA1 | |
| SCHEMBL16410352 | 0.80 | MTNR1A (0.48) | ALDH1A1GAAGFERMAPTHPGD | |
| SCHEMBL10314521 | 0.80 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AMAPTTSHR | |
| SCHEMBL15031152 | 0.73 | TRPA1 (0.43) | NPC1RAB9ATRPA1SLC6A2SLC6A4 | |
| SCHEMBL7590349 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GAAGFERMAPTHPGD | |
| SCHEMBL4568027 | 0.72 | CYP17A1 (0.38) | GAA | |
| SCHEMBL23442587 | 0.71 | TAAR1 (0.41) | ALDH1A1GAANPC1RAB9ATRPA1 | |
| SCHEMBL13634975 | 0.71 | SLC6A2 (0.43) | ALDH1A1GAAGFERTRPA1SLC6A2 | |
| SCHEMBL9778643 | 0.70 | GAA (0.52) | ALDH1A1GAARAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474530-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |