Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032220 | 0.90 | RAB9A (0.47) | LMNASMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL1030274 | 0.76 | POLB (0.46) | LMNARAB9AALDH1A1HPGDGAA | |
| SCHEMBL1032230 | 0.73 | ADORA3 (0.55) | LMNASMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL1032207 | 0.73 | ADORA3 (0.40) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL1027475 | 0.72 | NPC1 (0.44) | LMNANPC1RAB9AALOX15MAPK1 | |
| SCHEMBL1031744 | 0.71 | NPC1 (0.49) | LMNANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1031918 | 0.70 | ALDH1A1 (0.47) | LMNASMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL1031580 | 0.69 | ALDH1A1 (0.55) | LMNASMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1031541 | 0.69 | RAB9A (0.53) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1027476 | 0.68 | ALDH1A1 (0.47) | LMNAHTTALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |