SCHEMBL1031946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034305	0.86	KMO (0.49)	MEN1KMT2ARXFP1MAPTKMO
	SCHEMBL1033871	0.83	FGFR4 (0.51)	MEN1KMT2ARXFP1MAPTKMO
	SCHEMBL1033800	0.83	KMO (0.47)	KDRMEN1KMT2ARXFP1MAPT
	SCHEMBL1031638	0.81	ALDH1A1 (0.47)	RXFP1MAPTKMOFGFR4MAPKAPK2
	SCHEMBL12673319	0.81	PARP1 (0.61)	MEN1KMT2ARXFP1NNMTKDM4E
	SCHEMBL1034072	0.81	JAK2 (0.51)	KDRRXFP1MAPTKMOEGLN1
	SCHEMBL1033644	0.81	FGFR4 (0.56)	MEN1KMT2ARXFP1KMOFGFR4
	SCHEMBL1052702	0.81	KCNQ3 (0.60)	RXFP1FGFR4MAPKAPK2EGLN1
	SCHEMBL1034065	0.81	RXFP1 (0.53)	MEN1KMT2ARXFP1MAPTRAB9A
	SCHEMBL1033391	0.80	SIRT2 (0.50)	KMT2ARXFP1MAPTKMOFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.