SCHEMBL1052702

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1033800	0.86	KMO (0.47)	KCNQ3KCNQ2KCNE1KCNQ1CA12
	SCHEMBL1034065	0.85	RXFP1 (0.53)	CA12CA1CA2CA9PARP1
	SCHEMBL1032356	0.84	CSF1R (0.54)	CSF1RBRAFMAPK14RXFP1EGLN1
	SCHEMBL1031638	0.83	ALDH1A1 (0.47)	FGFR4MAPKAPK2CA12CA1CA2
	SCHEMBL1034072	0.83	JAK2 (0.51)	CA12CA1CA2CA9CSF1R
	SCHEMBL1033644	0.83	FGFR4 (0.56)	FGFR4MAPKAPK2PARP1RXFP1NFKB1
	SCHEMBL1034305	0.82	KMO (0.49)	FGFR4MAPKAPK2CA12CA1CA2
	SCHEMBL1032169	0.82	HIF1A (0.44)	KCNQ3KCNQ2KCNE1KCNQ1DHODH
	SCHEMBL12673179	0.81	PARP1 (0.61)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5
	SCHEMBL1031946	0.81	KDR (0.47)	FGFR4MAPKAPK2RXFP1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.