Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105652 | 1.00 | LMNA (0.43) | LMNAPLA2G7ABL1PDGFRAS1PR4 | |
| SCHEMBL18888856 | 0.90 | PLA2G7 (0.51) | LMNAPLA2G7ABL1PDGFRAS1PR4 | |
| SCHEMBL18889770 | 0.86 | ACHE (0.42) | PLA2G7ABL1PDGFRAS1PR4HSD17B1 | |
| SCHEMBL2546632 | 0.82 | ABL1 (0.38) | LMNAPLA2G7ABL1PDGFRAS1PR4 | |
| SCHEMBL18889559 | 0.81 | MAPT (0.43) | LMNANPSR1MAPTMAPK14NPC1 | |
| SCHEMBL1363337 | 0.79 | PRSS1 (0.52) | LMNAPRSS1PRSS2PRSS3MAPT | |
| SCHEMBL31484336 | 0.79 | PRSS1 (0.52) | LMNAPRSS1PRSS2PRSS3MAPT | |
| SCHEMBL18889295 | 0.77 | MKNK1 (0.44) | PLA2G7ABL1PDGFRAMAPK14 | |
| SCHEMBL8821558 | 0.77 | ABL1 (0.33) | ABL1PDGFRAMAPTNPC1RAB9A | |
| SCHEMBL2220714 | 0.76 | NR1H4 (0.41) | PLA2G7ABL1PDGFRAS1PR4HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018125-B2 | Diethylzinc composition, method for heat stabilization, and compound for heat stabilization | TOSOH FINECHEM CORPORATION (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20140228207-A1 | DIETHYLZINC COMPOSITION, METHOD FOR HEAT STABILIZATION, AND COMPOUND FOR HEAT STABILIZATION | TOSOH FINECHEM CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| US-8722561-B2 | Diethylzinc composition, method for heat stabilization, and compound for heat stabilization | TOSOH FINECHEM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20120184432-A1 | DIETHYLZINC COMPOSITION, METHOD FOR HEAT STABILIZATION, AND COMPOUND FOR HEAT STABILIZATION | TOSOH FINECHEM CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228207-A1 | DIETHYLZINC COMPOSITION, METHOD FOR HEAT STABILIZATION, AND COMPOUND FOR HEAT STABILIZATION | TBCD, HELZ, DKC1 | LMNA 1809/4885PLA2G7 4322/4885ABL1 2489/4885 |
| US-20120184432-A1 | DIETHYLZINC COMPOSITION, METHOD FOR HEAT STABILIZATION, AND COMPOUND FOR HEAT STABILIZATION | TBCD, HELZ, DKC1 | LMNA 1809/4885PLA2G7 4322/4885ABL1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.