SCHEMBL103216

SCHEMBL103216

C=CC(=O)Oc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.51
MMP3 P08254 7/20 0.48
MMP1 P03956 1/20 0.48
MMP9 P14780 1/20 0.48
MMP13 P45452 1/20 0.48
THRB P10828 3/20 0.46
HDAC2 Q92769 2/20 0.44
HDAC1 Q13547 1/20 0.44
F2 P00734 1/20 0.44
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PARP2 Q9UGN5 1/20 0.44
MGLL Q99685 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343191 0.95 THRB (0.50) MMP2MMP3MMP1MMP9MMP13
SCHEMBL816437 0.90 THRB (0.46) MMP2THRBF2PARP15PARP10
SCHEMBL13904878 0.89 HDAC2 (0.56) MMP2MMP3MMP1MMP9MMP13
SCHEMBL18328879 0.85 PPARD (0.43) MMP2THRBF2PARP15PARP10
SCHEMBL12354572 0.85 ALDH1A1 (0.50) THRBF2PARP15PARP10PARP2
SCHEMBL15695636 0.85 THRB (0.58) THRB
SCHEMBL802752 0.85 THRB (0.58) THRB
SCHEMBL12404406 0.84 MMP2 (0.45) MMP2MMP3MMP1MMP9MMP13
SCHEMBL29321770 0.84 MMP2 (0.48) MMP2MMP3MMP1MMP9MMP13
SCHEMBL29316093 0.83 MMP2 (0.50) MMP2MMP3MMP1MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7017938-A None JP disclosed
CN-115103387-B Antenna engineering parameter acquisition and abnormality alarm device and method 福建省邮电规划设计院有限公司 2025-06-24 CN disclosed
EP-3778171-B1 METHOD FOR MANUFACTURING RESIN THIN FILM STRIPPED PIECES ZEON CORP (JP) 2024-06-26 EP disclosed
CN-117327362-A Curable resin composition 东京应化工业株式会社 2024-01-02 CN disclosed
CN-111989317-B Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, and polarizing plate 日本瑞翁株式会社 2023-12-01 CN disclosed
WO-2023190481-A1 IDENTIFICATION MEDIUM AND PRODUCT 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023190483-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
WO-2023189966-A1 IDENTIFICATION MEDIUM AND ARTICLE 日本ゼオン株式会社 2023-10-05 WO disclosed
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed
US-6562259-B1 Photopolymerizable liquid crystal monomer is a 4-(4-(alkyloxycarbonyloxy)benzoyloxy)phenyl acrylate; optical head employing the optical element as a polarizing hologram element ASAHI GLASS COMPANY, LIMITED (JP) 2003-05-13 US disclosed
EP-0955348-B1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME ASAHI GLASS CO LTD (JP) 2002-10-23 EP disclosed
US-6180028-B1 ACRYLATED ESTERS ASAHI GLASS COMPANY LTD. (JP) 2001-01-30 US disclosed
EP-0955348-A1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME Asahi Glass Company Ltd. (JP) 1999-11-10 EP disclosed
JP-H0717938-A LIQUID CRYSTAL DEVICE AND NOVEL ACRYLATE COMPOUND DAINIPPON INK & CHEM INC 1995-01-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof AFF1, CNKSR1, LEF1 MMP2 4565/4885MMP3 3127/4885MMP1 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.