Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637910 | 0.76 | TP53 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL1027476 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTHSD17B10RECQLTAS1R3 | |
| SCHEMBL1030586 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL1027735 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL1027398 | 0.73 | CNR2 (0.54) | ALDH1A1 | |
| SCHEMBL1032165 | 0.73 | TSHR (0.49) | ALDH1A1 | |
| SCHEMBL1030344 | 0.73 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL1031680 | 0.70 | HPGDS (0.48) | ALDH1A1MEN1KMT2ADHODHTAS1R3 | |
| SCHEMBL4100978 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL1028261 | 0.68 | TAS1R3 (0.45) | ALDH1A1MEN1KMT2AHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |