Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10323087 | 0.78 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL10323010 | 0.76 | KMT2A (0.38) | — | |
| Hydrochloric Acid SCHEMBL10323618 | 0.73 | HTR1D (0.33) | HTR1DHTR1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL1225851 | 0.63 | RAPGEF4 (0.46) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL1823173 | 0.63 | MAOA (0.39) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL27995904 | 0.62 | HRH3 (0.54) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL1316919 | 0.62 | HTR1D (0.48) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL327084 | 0.60 | HRH3 (0.41) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL28489168 | 0.60 | HRH3 (0.41) | HTR1DHTR1BCYP11B1CYP11B2HRH3 | |
| SCHEMBL111999 | 0.58 | HRH3 (0.40) | HTR1DHTR1BCYP11B1CYP11B2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20120184693-A1 | ETHYLENE POLYMER PREPARATION METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | AP2A1, AP1M1, ME1 | HTR1D 1325/4885HTR1B 1546/4885CYP11B1 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.