SCHEMBL10324686

SCHEMBL10324686

O=C(O)OCC(CO)OC(=O)Cl

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 8/20 0.44
PRKCE Q02156 1/20 0.39
PRKCQ Q04759 1/20 0.39
PRKCD Q05655 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10714766 0.87 PRKCA (0.47) PRKCAPRKCEPRKCQPRKCD
SCHEMBL2266760 0.85 PRKCA (0.48) PRKCAPRKCEPRKCQPRKCD
SCHEMBL30585906 0.85 PRKCA (0.48) PRKCAPRKCEPRKCQPRKCD
SCHEMBL6841475 0.79
SCHEMBL1357083 0.79 PRKCA (0.44) PRKCAPRKCEPRKCQPRKCD
SCHEMBL4879570 0.79 PRKCA (0.56) PRKCAPRKCEPRKCQPRKCD
SCHEMBL15124570 0.78 PRKCA (0.47) PRKCAPRKCEPRKCQPRKCD
SCHEMBL6230224 0.75 ALDH1A1 (0.35) PRKCA
SCHEMBL1444732 0.75 PRKCA (0.42) PRKCAPRKCEPRKCQPRKCD
SCHEMBL289553 0.73 TSHR (0.44) PRKCAPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253815-B1 ISOCYANATE-FREE SYNTHESIS OF CARBONATE-MODIFIED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-06-15 EP disclosed
US-10202488-B2 Isocyanate-free synthesis of carbonate-modified polymers EVONIK DEGUSSA GMBH (DE) 2019-02-12 US disclosed
US-20170355814-A1 ISOCYANATE-FREE SYNTHESIS OF CARBONATE-MODIFIED POLYMERS EVONIK OPERATIONS GMBH (DE) 2017-12-14 US disclosed
EP-2797908-B1 PREPARING CYCLOCARBONATE-FUNCTIONALIZED COMPOUNDS BASF SE (DE) 2015-07-15 EP disclosed
US-9079871-B2 Preparing cyclocarbonate-functionalized compounds BASF SE (DE) 2015-07-14 US disclosed
US-20140378689-A1 PREPARING CYCLOCARBONATE-FUNCTIONALIZED COMPOUNDS BASF S.E. (DE) 2014-12-25 US disclosed
EP-2797908-A1 PREPARING CYCLOCARBONATE-FUNCTIONALIZED COMPOUNDS BASF SE (DE) 2014-11-05 EP disclosed
WO-2013098030-A1 PREPARING CYCLOCARBONATE-FUNCTIONALIZED COMPOUNDS BASF SE (DE) 2013-07-04 WO disclosed
US-20120238661-A1 Processes for the Synthesis of Compounds from Cyclic Carbonates COGNIS IP MANAGEMENT GMBH (DE) 2012-09-20 US disclosed
WO-2012095293-A2 PROCESS FOR THE SYNTHESIS OF COMPOUNDS FROM CYCLIC CARBONATES COGNIS IP MANAGEMENT GMBH (DE) 2012-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378689-A1 PREPARING CYCLOCARBONATE-FUNCTIONALIZED COMPOUNDS POLR2H, C9, POLR2E PRKCA 2487/4885PRKCE 2512/4885PRKCQ 2465/4885
US-20120238661-A1 Processes for the Synthesis of Compounds from Cyclic Carbonates GK, CRYZ, ELOC PRKCA 543/4885PRKCE 226/4885PRKCQ 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.