SCHEMBL10324852

SCHEMBL10324852

NC(N)=Nc1cccc2c1P(O)(=S)Oc1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 2/20 0.37
HTR3B O95264 2/20 0.37
HTR3A P46098 2/20 0.37
HTR3D Q70Z44 2/20 0.37
HTR3C Q8WXA8 2/20 0.37
PLAU P00749 2/20 0.33
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
RAD52 P43351 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13835200 0.83 HTR3E (0.37) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10324737 0.77 ALDH1A1 (0.34)
Guanidine SCHEMBL10324850 0.68
SCHEMBL930972 0.68 KDM4E (0.31)
SCHEMBL887329 0.66 KDM4E (0.34) PKM
Ammonia Solution, Strong SCHEMBL932033 0.66
SCHEMBL13278323 0.62 ALDH1A1 (0.34)
SCHEMBL18076604 0.60 KDM4E (0.36) PKM
SCHEMBL14901026 0.59 KDM4E (0.34) PKM
SCHEMBL30426151 0.59 GPR84 (0.52) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184635-A1 Flameproof expandable polymerizates Sunpor Kunststoff Ges m.b.H. (AT) 2012-07-19 US disclosed
CN-102597091-A Flame retardant expandable polymers SUNPOR KUNSTSTOFF GMBH 2012-07-18 CN disclosed