SCHEMBL10325520

SCHEMBL10325520

OC[C@H]1OC(O)[C@@](O)(CF)[C@@H](O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
GBA1 P04062 2/20 0.35
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 1/20 0.35
OGA O60502 4/20 0.35
LGALS1 P09382 2/20 0.34
LGALS3 P17931 2/20 0.34
LGALS9 O00182 1/20 0.34
LGALS8 O00214 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10345005 1.00 ALDH1A1 (0.35) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL10325111 1.00 ALDH1A1 (0.35) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL3620661 0.79 ALDH1A1 (0.34) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL8013317 0.79 ALDH1A1 (0.34) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL17982748 0.79 ALDH1A1 (0.34) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL8509956 0.79 ALDH1A1 (0.34) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL20607659 0.78 ALDH1A1 (0.33) ALDH1A1TSHRGBA1LMNATDP1
SCHEMBL27818667 0.76 LGALS1 (0.36) ALDH1A1TSHRLMNATDP1GAA
SCHEMBL17610102 0.76 LGALS1 (0.36) ALDH1A1TSHRLMNATDP1GAA
SCHEMBL6837637 0.76 LGALS1 (0.36) ALDH1A1TSHRLMNATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-04-27 US disclosed
EP-4121060-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF Board of Regents, The University of Texas System (US) 2023-01-25 EP disclosed
CN-115515601-A Methods of treating viral infections with hexose-type monosaccharides and analogs thereof 得克萨斯大学体系董事会 2022-12-23 CN disclosed
WO-2021188586-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-09-23 WO disclosed
EP-2663314-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES The University of Texas M.D. Anderson Cancer (US) 2013-11-20 EP disclosed
US-20120276108-A1 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO (US) 2012-11-01 US disclosed
WO-2012097052-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO, LLC (US) 2012-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130134-A1 METHOD OF TREATING VIRAL INFECTIONS WITH HEXOSE TYPE MONOSACCHARIDES AND ANALOGS THEREOF G6PD, FBP1, ALDOA ALDH1A1 525/4885TSHR 3732/4885GBA1 56/4885
US-20120276108-A1 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES IGF1R, IRS1, IGFBP1 ALDH1A1 1738/4885TSHR 1896/4885GBA1 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.