Acetic Acid

Acetic Acid

SCHEMBL1033265

CC(=O)[O-].Cc1ccccc1[P+](c1ccccc1C)(c1ccccc1C)c1ccccc1C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
EPHX1 P07099 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA1 P00915 2/20 0.35
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MYC P01106 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27448930 0.85 ALDH1A1 (0.39) ALDH1A1HPGDEPHX1TSHRACHE
Acetic Acid SCHEMBL9068177 0.85 ALDH1A1 (0.39) ALDH1A1HPGDEPHX1TSHRACHE
Benzoic Acid SCHEMBL7872910 0.84 CA2 (0.57) ALDH1A1HPGDEPHX1TSHRRAB9A
SCHEMBL7874669 0.84 TSHR (0.47) ALDH1A1TSHRACHETDP1CA1
SCHEMBL30634705 0.83 TSHR (0.53) ALDH1A1TSHRACHETDP1CA1
Acetic Acid SCHEMBL7606377 0.81 ALDH1A1 (0.40) ALDH1A1TSHRNPC1RAB9A
Water SCHEMBL4384424 0.81 TSHR (0.50) ALDH1A1TSHRACHETDP1CA1
Hydrochloric Acid SCHEMBL11444635 0.81 TSHR (0.50) ALDH1A1TSHRACHETDP1CA1
Fluoride Ion SCHEMBL943596 0.81 TSHR (0.50) ALDH1A1TSHRACHETDP1CA1
Bromide SCHEMBL7873025 0.81 TSHR (0.50) ALDH1A1TSHRACHETDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122613-B1 Method for the production of polycarbonates GENERAL ELECTRIC COMPANY (US) 2006-10-17 US claimed
EP-1578840-A1 METHOD FOR THE PRODUCTION OF POLYCARBONATES General Electric Company (US) 2005-09-28 EP claimed
WO-2004060963-A1 METHOD FOR THE PRODUCTION OF POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-07-22 WO claimed
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
US-20250340697-A1 METHOD FOR THE MANUFACTURE OF POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-11-06 US disclosed
EP-4532597-A1 METHOD FOR THE MANUFACTURE OF POLYCARBONATE SABIC Global Technologies B.V. (NL) 2025-04-09 EP disclosed
US-12084542-B2 Polycarbonate compositions with improved oxidation stability and methods of manufacturing the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-09-10 US disclosed
US-12077635-B2 Method for the manufacture of polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-09-03 US disclosed
US-11879035-B2 Polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-23 US disclosed
US-11859048-B2 Oligomeriser with improved mixing performance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-02 US disclosed
EP-3645158-B1 OLIGOMERISER WITH IMPROVED MIXING PERFORMANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-12-20 EP disclosed
WO-2023233041-A1 METHOD FOR THE MANUFACTURE OF POLYCARBONATE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-12-07 WO disclosed
US-6228973-B1 REACTING A DIHYDRIC PHENOL AND A DIHYDROCARBYL CARBONATE BY SOLVENT-FREE MELT POLYMERIZATION CATALYZED BY A TETRAORGANOPHOSPHONIUM SALT AND A LOWER CONCENTRATION OF ALKALI/ALKALINE EARTH COMPOUND; BY-PRODUCT INHIBITION GENERAL ELECTRIC COMPANY 2001-05-08 US disclosed
EP-1069146-A1 POLYCARBONATE AND OPTICAL MATERIAL Idemitsu Petrochemical Co., Ltd. (JP) 2001-01-17 EP disclosed
EP-1035150-A1 COPOLYCARBONATE AND PROCESS FOR PRODUCING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-09-13 EP disclosed
EP-0702044-B1 Polycarbonate redistribution method GEN ELECTRIC (US) 2000-05-03 EP disclosed
EP-0702044-A1 Polycarbonate redistribution method GENERAL ELECTRIC COMPANY (US) 1996-03-20 EP disclosed
US-5459226-A Melt extrusion in presence of tetraorganophosphonium carboxylate salt GENERAL ELECTRIC COMPANY (US) 1995-10-17 US disclosed
EP-0671428-A1 Method for making polycarbonates GENERAL ELECTRIC COMPANY (US) 1995-09-13 EP disclosed
US-5412061-A Polycarbonate melt condensation synthesis using a tetraorganophosphonium carboxylate salt catalyst GENERAL ELECTRIC COMPANY (US) 1995-05-02 US disclosed