Fluoride Ion

Fluoride Ion

SCHEMBL943596

Cc1ccccc1[P+](c1ccccc1C)(c1ccccc1C)c1ccccc1C.[F-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ACHE P22303 3/20 0.50
ALDH1A1 P00352 4/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
ESR1 P03372 1/20 0.39
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30634705 0.97 TSHR (0.53) TSHRACHEALDH1A1CA1CA2
Bromide SCHEMBL7873025 0.94 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL11444635 0.94 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
Water SCHEMBL4384424 0.94 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL7874669 0.92 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL7874600 0.85 ACHE (0.41) TSHRACHEALDH1A1CA1CA2
Phenol SCHEMBL7872892 0.83 TSHR (0.39) TSHRACHEALDH1A1CA1CA2
Bromide SCHEMBL7886102 0.79 TSHR (0.41) TSHRACHEALDH1A1CA1CA2
Iodide SCHEMBL9067572 0.74 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL1955171 0.74 TSHR (0.47) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3381903-B1 PENTAFLUOROSULFANYLPYRIDINE UBE INDUSTRIES (JP) 2020-12-30 EP disclosed
US-10676439-B2 Pentafluorosulfanyl pyridine UBE INDUSTRIES, LTD. (JP) 2020-06-09 US disclosed
US-20180370917-A1 PENTAFLUOROSULFANYL PYRIDINE UBE CORPORATION (JP) 2018-12-27 US disclosed
EP-3381903-A1 PENTAFLUOROSULFANYLPYRIDINE UBE Industries, Ltd. (JP) 2018-10-03 EP disclosed
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 US disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
WO-2010014665-A1 METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2010-02-04 WO disclosed
EP-2137144-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T Research, Inc. (US) 2009-12-30 EP disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
WO-2008118787-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM & T RESEARCH, INC. (US) 2008-10-02 WO disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA TSHR 76/4885ACHE 3969/4885ALDH1A1 2190/4885
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 TSHR 484/4885ACHE 3210/4885ALDH1A1 3759/4885
US-10676439-B2 Pentafluorosulfanyl pyridine AFF4, Q6ZSR9, AFF2 TSHR 1831/4885ACHE 3695/4885ALDH1A1 3305/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA TSHR 76/4885ACHE 3969/4885ALDH1A1 2190/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA TSHR 76/4885ACHE 3969/4885ALDH1A1 2190/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA TSHR 76/4885ACHE 3969/4885ALDH1A1 2190/4885
US-20180370917-A1 PENTAFLUOROSULFANYL PYRIDINE AFF4, Q6ZSR9, AFF2 TSHR 1831/4885ACHE 3695/4885ALDH1A1 3305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.