Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790756 | 0.79 | S100A4 (0.36) | TDP1HSD17B10GAALMNAMAPT | |
| SCHEMBL4390654 | 0.75 | CYP3A4 (0.32) | PTGS2HSD17B10POLBMAPTRAB9A | |
| SCHEMBL8868904 | 0.72 | MEN1 (0.52) | TDP1HSD17B10POLBLMNAMAPT | |
| SCHEMBL8881481 | 0.72 | MCHR1 (0.43) | GAALMNAMAPTTSHRMAPK1 | |
| SCHEMBL223271 | 0.72 | POLB (0.55) | HSD17B10POLBGAALMNAMAPT | |
| SCHEMBL514437 | 0.71 | ALDH1A1 (0.37) | HSD17B10POLBGAALMNAMAPT | |
| SCHEMBL23734864 | 0.71 | MTNR1A (0.50) | TDP1PTGS2POLBMAPTTSHR | |
| SCHEMBL8505956 | 0.71 | APOBEC3G (0.40) | POLBMAPTKMT2A | |
| SCHEMBL7394194 | 0.70 | L3MBTL1 (0.38) | LMNARAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28867399 | 0.69 | ALDH1A1 (0.33) | HSD17B10POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |