Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.46 |
| ▸ | BMP1 | P13497 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417371 | 0.94 | PTPN1 (0.49) | PSMB1PSMB5PSMB2BMP1HDAC8 | |
| SCHEMBL8910628 | 0.87 | KMT2A (0.56) | ITGB3ITGA2B | |
| SCHEMBL19051462 | 0.82 | BMP1 (0.54) | BMP1 | |
| SCHEMBL9417356 | 0.82 | HDAC1 (0.56) | HDAC8 | |
| SCHEMBL11012331 | 0.82 | REN (0.51) | PSMB1PSMB5PSMB2BMP1PTPN1 | |
| SCHEMBL28011820 | 0.82 | BMP1 (0.48) | PTGER4BMP1ITGB3ITGA2B | |
| SCHEMBL2177818 | 0.82 | BMP1 (0.48) | PTGER4BMP1ITGB3ITGA2B | |
| SCHEMBL9800635 | 0.80 | KMT2A (0.63) | HDAC8ITGB3ITGA2BPTPN1 | |
| SCHEMBL10443977 | 0.80 | CTSL (0.57) | ITGB3ITGA2B | |
| SCHEMBL7432056 | 0.80 | FOLH1 (0.61) | PTGER4BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295294-A4 | PEPTIDYLAMINODIOLS. | ABBOTT LAB (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0295294-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-12-21 | — | — | EP | disclosed |
| WO-1988005050-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-07-14 | — | — | WO | disclosed |