Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417279 | 0.93 | CTSS (0.40) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL1562599 | 0.83 | POLB (0.44) | CTSSCTSLCTSBPOLBCTSK | |
| SCHEMBL1562598 | 0.83 | POLB (0.44) | CTSSCTSLCTSBPOLBCTSK | |
| SCHEMBL10555105 | 0.83 | CTSL (0.56) | CTSSCTSLCTSBPOLBCTSK | |
| SCHEMBL9417280 | 0.77 | SMN1; SMN2 (0.55) | CTSSSMN1; SMN2 | |
| SCHEMBL9417277 | 0.77 | SMN1; SMN2 (0.55) | CTSSSMN1; SMN2 | |
| SCHEMBL7295361 | 0.77 | SMN1; SMN2 (0.55) | CTSSSMN1; SMN2 | |
| SCHEMBL7441871 | 0.76 | CTSS (0.53) | CTSSCTSLCTSBPOLBCTSK | |
| SCHEMBL9417266 | 0.76 | CTSS (0.53) | CTSSCTSLCTSBPOLBCTSK | |
| Water SCHEMBL10422512 | 0.74 | REN (0.52) | CTSSPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295294-A4 | PEPTIDYLAMINODIOLS. | ABBOTT LAB (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0295294-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-12-21 | — | — | EP | disclosed |
| WO-1988005050-A1 | PEPTIDYLAMINODIOLS | ABBOTT LABORATORIES (US) | 1988-07-14 | — | — | WO | disclosed |