Water

Water

SCHEMBL3249386

N#[N+]c1ccc(S(=O)(=O)O)cc1.[OH-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
ALDH1A1 P00352 6/20 0.48
TSHR P16473 3/20 0.48
NT5E P21589 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
TDP1 Q9NUW8 3/20 0.43
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41
NAPRT Q6XQN6 1/20 0.38
HSD17B10 Q99714 4/20 0.36
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HPGD P15428 1/20 0.33
TIMP3 P35625 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937040 0.98 LMNA (0.52) LMNAALDH1A1TSHRNT5ESMN1; SMN2
Hydrochloric Acid SCHEMBL3425485 0.95 LMNA (0.50) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8573193 0.90 LMNA (0.45) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL9333537 0.88 ALDH1A1 (0.46) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL10337307 0.83 TSHR (0.55) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL9333324 0.82 ALDH1A1 (0.42) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL11216403 0.82 TTR (0.50) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL11035060 0.79 TTR (0.40) LMNAALDH1A1TSHRNT5ESMN1; SMN2
Betaine SCHEMBL8843972 0.79 TSHR (0.44) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8275191 0.78 ALDH1A1 (0.46) LMNAALDH1A1TSHRPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180099905-A1 WATERFASTNESS, SMEARFASTNESS, WEAR RESISTANCE, TOUGHNESS AND OVERALL MATERIAL DURABILITY ENHANCING NANO ADDITIVE HK INVESTMENT PRODUCTION TRADING (VN) 2018-04-12 US disclosed
EP-1664215-B1 RECORDING INK FOR INK-JET RECORDING APPARATUS, AND, INK CARTRIDGE, INK-JET RECORDING APPARATUS, INK-JET RECORDING PROCESS,AND RECORDED MATTER RICOH CO LTD (JP) 2015-11-04 EP disclosed
EP-1225205-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-10-06 EP disclosed
EP-0909296-B2 MODIFIED CARBON PRODUCTS AND AMPHIPHILIC IONS CONTAINING COMPOSITIONS CABOT CORP (US) 2010-05-19 EP disclosed
EP-1942156-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-04-14 EP disclosed
EP-1942156-A1 Carbon black reacted with diazonium salts and products Cabot Corporation (US) 2008-07-09 EP disclosed
US-7370952-B2 Ink, and, inkjet recording process, ink cartridge, recording unit, and inkjet recording apparatus using the ink RICOH COMPANY, LTD. (JP) 2008-05-13 US disclosed
EP-1405882-B1 INK JET RECORDING INK SET RICOH KK (JP) 2007-11-21 EP disclosed
US-7294185-B2 In absence of exterior applies electrical current; wear resistance CABOT CORPORATION (US) 2007-11-13 US disclosed
US-7278726-B2 Ink jet recording ink set RICOH COMPANY, LTD. (JP) 2007-10-09 US disclosed
EP-0797637-A1 AQUEOUS INKS AND COATINGS CONTAINING MODIFIED CARBON PRODUCTS CABOT CORPORATION (US) 1997-10-01 EP disclosed
US-5672198-A CONTAINING IONIZABLE GROUP CABOT CORPORATION (US) 1997-09-30 US disclosed
US-5630868-A REACTED WITH DIAZONIUM SALT; PRINT QUALITY CABOT CORPORATION (US) 1997-05-20 US disclosed
US-5575845-A Carbon black products for coloring mineral binders CABOT CORPORATION (US) 1996-11-19 US disclosed
US-5571311-A Ink jet ink formulations containing carbon black products CABOT CORPORATION (US) 1996-11-05 US disclosed
WO-1996018689-A1 CARBON BLACK PRODUCTS FOR COLORING MINERAL BINDERS CABOT CORPORATION (US) 1996-06-20 WO disclosed
WO-1996018456-A2 GEL COMPOSITION CONTAINING CARBONACEOUS COMPOUND CABOT CORPORATION (US) 1996-06-20 WO disclosed
WO-1996018688-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed
WO-1996018696-A1 AQUEOUS INKS AND COATINGS CONTAINING MODIFIED CARBON PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed
WO-1996018695-A1 INK JET INK FORMULATIONS CONTAINING MODIFIED CARBON PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed