Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HPD | P32754 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337475 | 0.79 | CDK2 (0.31) | ALDH1A1CDK2HPD | |
| SCHEMBL11116038 | 0.76 | TSHR (0.43) | ALDH1A1KMT2AMEN1MAPK1CDK2 | |
| SCHEMBL10972478 | 0.69 | MAPT (0.41) | ALDH1A1MAPTCDK2HPGDTP53 | |
| SCHEMBL11090841 | 0.67 | HPGD (0.48) | ALDH1A1KMT2APOLBMAPTMEN1 | |
| SCHEMBL9172243 | 0.65 | CTSD (0.50) | ALDH1A1KMT2APOLBMAPTHPGD | |
| SCHEMBL23294948 | 0.63 | TSHR (0.51) | ALDH1A1KMT2APOLBMAPTMEN1 | |
| SCHEMBL29588719 | 0.63 | TSHR (0.51) | ALDH1A1KMT2APOLBMAPTMEN1 | |
| SCHEMBL17966270 | 0.63 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL26401595 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBMAPTMEN1 | |
| SCHEMBL30402800 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370644-A2 | Herbicidal compounds | ZENECA LIMITED (GB) | 1990-05-30 | — | — | EP | disclosed |
| EP-0355049-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1990-02-21 | — | — | EP | disclosed |