Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148896 | 0.81 | KAT6A (0.65) | MAOAPOLBPTGS2KAT6AKDM4E | |
| SCHEMBL7990845 | 0.81 | FLT1 (0.65) | MAOAMAOBPOLBPTGS2ALDH1A1 | |
| SCHEMBL13228671 | 0.80 | POLB (0.59) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL27785648 | 0.78 | ALDH1A1 (0.64) | MAOAMAOBPTGS2ALDH1A1KDM4E | |
| SCHEMBL27603191 | 0.76 | ALDH1A1 (0.62) | MAOAMAOBPTGS2ALDH1A1KDM4E | |
| SCHEMBL7042272 | 0.76 | POLB (0.63) | MAOAMAOBPOLBPTGS2ALDH1A1 | |
| SCHEMBL20233293 | 0.76 | KAT6A (0.78) | ALDH1A1KAT6AGAAFLT1FLT4 | |
| SCHEMBL31456325 | 0.75 | POLB (0.67) | MAOAMAOBPOLBPTGS2ALDH1A1 | |
| SCHEMBL28377074 | 0.74 | ALDH1A1 (0.55) | MAOAMAOBPOLBPTGS2ALDH1A1 | |
| SCHEMBL16380418 | 0.74 | PTGS2 (0.64) | MAOAMAOBPOLBPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2200662-A | — | — | None | — | — | JP | disclosed |
| JP-H02200662-A | NEW HYDRAZIDE DERIVATIVE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1990-08-08 | — | — | JP | disclosed |