Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL7796886 | 0.87 | TSHR (0.70) | TSHRHSD17B10NAPRTGFERTP53 | |
| SCHEMBL9075216 | 0.80 | MDM2 (0.41) | TSHRHSD17B10TP53EPHX1ALDH1A1 | |
| SCHEMBL9075007 | 0.78 | RAB9A (0.44) | TP53ALDH1A1HIF1AMAPTNPC1 | |
| Methyl Alcohol SCHEMBL11681702 | 0.77 | TSHR (0.88) | TSHRHSD17B10NAPRTGFERTP53 | |
| Benzene SCHEMBL17977991 | 0.76 | TSHR (1.00) | TSHRHSD17B10NAPRTTP53EPHX1 | |
| SCHEMBL4454 | 0.76 | — | — | |
| SCHEMBL19298582 | 0.76 | TSHR (1.00) | TSHRHSD17B10NAPRTTP53EPHX1 | |
| SCHEMBL3008675 | 0.76 | — | — | |
| Toluene SCHEMBL4094664 | 0.76 | LMNA (0.52) | TSHRTP53SMN1; SMN2ALDH1A1HPGD | |
| Biphenyl SCHEMBL27266761 | 0.76 | ALDH1A1 (0.43) | TSHRSMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |
| US-4210643-A | TREATING DIABETES MELLITUS WITH ETHANE-1-AMINO1,1-DIPHOSPHONIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4113861-A | FOR TREATMENT OF DIABETES BY AFFECTING CARBOHYDRATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4113862-A | FOR TREATMENT OF DIABETES BY AFFECTING CARBOHYDRATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |