SCHEMBL10340887

SCHEMBL10340887

C=CCc1ccc(O)c(F)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.68
GABRA1 P14867 8/20 0.66
GABRB2 P47870 8/20 0.66
ALDH1A1 P00352 3/20 0.66
CNR2 P34972 3/20 0.66
MAPT P10636 3/20 0.66
MEN1 O00255 2/20 0.66
GAA P10253 2/20 0.66
CNR1 P21554 2/20 0.66
KMT2A Q03164 2/20 0.66
PPARG P37231 2/20 0.66
PPARD Q03181 2/20 0.66
KDM4E B2RXH2 1/20 0.66
ALDH2 P05091 1/20 0.66
AKR1B1 P15121 1/20 0.66
HPGD P15428 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
TNKS O95271 1/20 0.59
PARP1 P09874 1/20 0.59
ALOX5 P09917 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9879571 0.85 CYP3A4 (0.55) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL11580187 0.84 XDH (0.68) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL1700963 0.82 XDH (0.44) XDHGABRA1GABRB2ALDH1A1CNR2
Hydroxychavicol SCHEMBL43300 0.81 XDH (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL12833024 0.81 XDH (0.52) XDHGABRA1GABRB2ALDH1A1CNR2
Hydroxychavicol SCHEMBL15676540 0.81 XDH (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
Magnolol SCHEMBL132477 0.79 GABRA1 (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
Magnolol SCHEMBL29538482 0.79 GABRA1 (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
Magnolol SCHEMBL29649179 0.79 GABRA1 (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL11762768 0.78 XDH (0.66) XDHGABRA1GABRB2ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124643-A Preparation of 3-fluorosalicylaldehyde UOP INC. (US) 1978-11-07 US claimed
CN-104326916-A Combined preparation and application of 2-fluoro-4-allyl-6-nitrophenol and 2-fluoro-4-nitro-6-allyl phenol UNIV QINGDAO AGRICULTURAL 2015-02-04 CN disclosed
WO-2011064789-A1 IMPROVED PROCESS FOR THE PREPARATION OF HALO-DIALKOXYBENZENES HIKAL LIMITED (IN) 2011-06-03 WO disclosed
CN-1009657-B LIQUID CRYSTAL MATERIALS CONTAINING BIPHENYL ESTERS AND DEVICES USING THEM SECR DEFENCE BRIT (GB) 1990-09-19 CN disclosed
US-4952337-A FERROELECTRIC MATERIALS THE SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM, OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1990-08-28 US disclosed
EP-0210215-B1 FLUORINATED PHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1990-03-14 EP disclosed
US-4769176-A Biphenyl esters and liquid crystal materials and devices containing them THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1988-09-06 US disclosed
EP-0210215-A1 Fluorinated phenyl esters and liquid crystal materials and devices containing them. SECR DEFENCE BRIT (GB) 1987-02-04 EP disclosed
CN-86101044-A Contain the liquid crystal mixed material of biphenyl ester class and the device that uses them 1986-12-17 CN disclosed
WO-1986004327-A1 BIPHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1986-07-31 WO disclosed
US-4366330-A A FLUOROPHENOL CAPABLE OF BEING REACTED WITH AN ARYL OR CYCLOALKYL CARBOXYLIC ACID TO PRODUCT AN ESTER BCH CHEMICALS LIMITED (GB) 1982-12-28 US disclosed
US-4124643-A Preparation of 3-fluorosalicylaldehyde UOP INC. (US) 1978-11-07 US disclosed
US-4124643-A Preparation of 3-fluorosalicylaldehyde UOP INC. (US) 1978-11-07 US disclosed