Hydroxychavicol

Hydroxychavicol

SCHEMBL43300

C=CCc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 1.00
ALDH1A1 P00352 5/20 0.73
GABRA1 P14867 4/20 0.73
GABRB2 P47870 4/20 0.73
MAPT P10636 4/20 0.73
GAA P10253 3/20 0.73
KDM4E B2RXH2 3/20 0.73
MEN1 O00255 2/20 0.73
CNR1 P21554 2/20 0.73
CNR2 P34972 2/20 0.73
KMT2A Q03164 2/20 0.73
PPARG P37231 2/20 0.73
PPARD Q03181 2/20 0.73
ALDH2 P05091 1/20 0.73
AKR1B1 P15121 1/20 0.73
HPGD P15428 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73
TNKS O95271 1/20 0.65
PARP1 P09874 1/20 0.65
ALOX5 P09917 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxychavicol SCHEMBL15676540 1.00 XDH (1.00) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL28050570 0.94 XDH (0.88) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL28378475 0.92 XDH (0.85) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL29440283 0.90 XDH (0.81) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL22717104 0.90 XDH (0.81) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL1657169 0.89 XDH (0.79) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL25287635 0.86 XDH (0.76) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL29414894 0.86 XDH (0.76) XDHALDH1A1GABRA1GABRB2MAPT
Hydroxychavicol SCHEMBL7856454 0.86 XDH (0.73) XDHALDH1A1GABRA1GABRB2MAPT
Magnolol SCHEMBL132477 0.84 GABRA1 (1.00) XDHALDH1A1GABRA1GABRB2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031592-A Application of dragon's blood and active ingredients thereof in preparation of drugs for treating heart failure 上海中医药大学 2026-05-15 CN claimed
EP-4727986-A1 ABRASIVE ARTICLE August Rüggeberg GmbH & Co. KG (DE) 2026-04-22 EP claimed
US-12558392-B1 Herbal oral compositions having the properties for supporting and enhancing musculoskeletal health and method of manufacturing the same Tran, Dang Huy (VN) 2026-02-24 US claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
EP-4619472-A1 MODIFIED PRECIPITATED SILICA, ITS MANUFACTURE AND USE RHODIA OPERATIONS (FR) 2025-09-24 EP claimed
WO-2025131235-A1 ABRASIVE ARTICLE AUGUST RÜGGEBERG GMBH & CO. KG (DE) 2025-06-26 WO claimed
CN-120116506-A Self-repairing TPU color-changing film and preparation process thereof 南通纳科达聚氨酯科技有限公司 2025-06-10 CN claimed
US-12312506-B2 Polymers for metal surface treatment SPECIALTY OPERATIONS FRANCE (FI) 2025-05-27 US claimed
CN-119639253-B Preparation method and application of multifunctional ZIF-8/polymer nanosphere pigment 德州学院 2025-05-16 CN claimed
CN-119978955-A Antioxidant copper rod and preparation method thereof 德阳杰创线缆机械有限责任公司 2025-05-13 CN claimed
WO-2001006995-A1 COSMETIC AGENTS CONTAINING HYDROXYCHAVICOL COGNIS DEUTSCHLAND GMBH (DE) 2001-02-01 WO claimed
EP-1048664-A2 Process for the synthesis of 5-allybenzodioxoles ENDURA S.p.A. (IT) 2000-11-02 EP claimed
US-6114298-A MICROEMULSION THE PROCTER & GAMBLE COMPANY (US) 2000-09-05 US claimed
US-6110883-A STABLE LIQUID AQUEOUS CLEANING COMPOSITIONS COMPRISING A SPECIFIED ZWITTERIONIC QUATERNARY AMMONIUM SURFACTANT, A PEROXYGEN BLEACH, FREE RADICAL SCAVENGER, CHELATING AGENT, PH BUFFER, ANTIMICROBIAL ESSENTIAL OIL AND SOLVENT THE PROCTER & GAMBLE COMPANY (US) 2000-08-29 US claimed
WO-1998021299-A1 AQUEOUS ALKALINE PEROXYGEN BLEACH-CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-05-22 WO claimed
EP-0843001-A1 Aqueous alkaline peroxygen bleach-containing compositions THE PROCTER & GAMBLE COMPANY (US) 1998-05-20 EP claimed
WO-1997002331-A1 LAUNDRY PRETREATMENT PEROXYGEN BLEACH WITH RADICAL SCAVENGER GIVING IMPROVED FABRIC/COLOR SAFETY THE PROCTER & GAMBLE COMPANY (US) 1997-01-23 WO claimed
EP-0752469-A1 Laundry pre-treatment with improved fabric/colour safety THE PROCTER & GAMBLE COMPANY (US) 1997-01-08 EP claimed
US-5473034-A Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby HYOGO PREFECTURAL GOVERNMENT (JP) 1995-12-05 US claimed
US-4107054-A NATURAL OR SYNTHETIC LUBRICANT - ALKENYLSUCCINIMIDE DISPERSANT - ANTHRANILIC ACID, ALKYLBENZOIC ACID, OR ALKYLCATECHOL AS RUST INHIBITOR CONTINENTAL OIL COMPANY (US) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558392-B1 Herbal oral compositions having the properties for supporting and enhancing musculoskeletal health and method of manufacturing the same COL2A1, COL1A1, ALPI XDH 2736/4885ALDH1A1 569/4885GABRA1 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.