Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341053 | 0.88 | SRD5A2 (0.44) | ATMTDP1L3MBTL1ALDH1A1SRD5A2 | |
| SCHEMBL6008685 | 0.88 | SRD5A2 (0.44) | ATMTDP1L3MBTL1ALDH1A1SRD5A2 | |
| SCHEMBL28055458 | 0.78 | PBRM1 (0.72) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL5685677 | 0.78 | PARP1 (0.53) | ATMTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL398594 | 0.78 | SRD5A2 (0.50) | ALDH1A1SRD5A2RAB9AKMT2ASTS | |
| SCHEMBL2882296 | 0.78 | PARP1 (0.53) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL5685417 | 0.78 | CES2 (0.57) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL2887787 | 0.78 | PARP1 (0.53) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL144448 | 0.78 | ALDH1A1 (0.70) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| SCHEMBL1535886 | 0.77 | ALDH1A1 (0.50) | ATMTDP1L3MBTL1ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912166-A | Melt blending | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| EP-0320894-A2 | Curable blends of fluoroelastomer and poly(ether-ketone-ketone) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-21 | — | — | EP | claimed |
| JP-1301744-A | — | — | None | — | — | JP | disclosed |
| US-4912166-A | Melt blending | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0320894-A3 | CURABLE BLENDS OF FLUOROELASTOMER AND POLY(ETHER-KETONE-KETONE) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| JP-H01301744-A | CURABLE BLEND OF FLUOROELASTOMER WITH POLY(ETHERKETONEKETONE) | E I DU PONT DE NEMOURS & CO | 1989-12-05 | — | — | JP | disclosed |
| EP-0320894-A2 | Curable blends of fluoroelastomer and poly(ether-ketone-ketone) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-21 | — | — | EP | disclosed |
| EP-0320894-A2 | Curable blends of fluoroelastomer and poly(ether-ketone-ketone) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-21 | — | — | EP | disclosed |