SCHEMBL6008685

SCHEMBL6008685

[O]c1ccc(C(=O)c2cc[c]cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.44
LMNA P02545 4/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 1/20 0.37
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RAB9A P51151 2/20 0.34
LTA4H P09960 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341053 1.00 SRD5A2 (0.44) SRD5A2LMNAMAPTHPGDESR1
SCHEMBL398594 0.88 SRD5A2 (0.50) SRD5A2MAPTHPGDHTTALDH1A1
SCHEMBL10340966 0.88 ATM (0.55) SRD5A2LMNAMAPTHPGDALDH1A1
SCHEMBL1535886 0.87 ALDH1A1 (0.50) SRD5A2LMNAMAPTHPGDESR1
SCHEMBL9579976 0.84 SRD5A2 (0.50) SRD5A2MAPTHPGDHTTALDH1A1
SCHEMBL23113194 0.81 LMNA (0.71) SRD5A2LMNAMAPTHPGDESR1
SCHEMBL2884665 0.81 SRD5A2 (0.71) SRD5A2ALDH1A1
SCHEMBL28753477 0.79 CA12 (0.48) SRD5A2LMNAMAPTHPGDESR1
SCHEMBL2882742 0.79 ALDH1A1 (0.73) SRD5A2LMNAHPGDPKMHTT
SCHEMBL3035196 0.79 LTA4H (0.57) SRD5A2LMNAMAPTHPGDESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2492022-B1 Non-stick coating LOOSER AG (CH) 2013-03-13 EP claimed
EP-1432752-B1 METHOD FOR THE SULPHONATION OF AROMATIC POLYMERS, POLYELECTROLYTES AND USE THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2006-03-08 EP claimed
US-20160053042-A1 Modified Polyaryletherketone Polymer (Paek) and Process To Obtain It UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) 2016-02-25 US disclosed
EP-2749300-A1 Modified polyaryletherketone polymer (PAEK) and process to obtain it Universidad Del Pais Vasco-Euskal Herriko Unibertsitatea (ES) 2014-07-02 EP disclosed
EP-0440923-B1 Polyolefin resin compositions and process for producing same SUMITOMO CHEMICAL CO (JP) 1997-06-04 EP disclosed
EP-0532893-A2 Depolymerization of polymers and their use in thermoset compositions and composites HERCULES INCORPORATED (US) 1993-03-24 EP disclosed