Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031736 | 0.94 | STAT3 (0.41) | STAT3SSTR5PARP1PARP2SYK | |
| SCHEMBL1035443 | 0.90 | AKT1 (0.41) | SSTR5F10CHEK2PRKAA2AKT1 | |
| SCHEMBL1034169 | 0.79 | HIF1A (0.51) | STAT3SSTR5F10AKT1HIF1A | |
| SCHEMBL2681885 | 0.79 | F10 (0.44) | STAT3F10CCR2BRAFHIF1A | |
| Hydrochloric Acid SCHEMBL2681741 | 0.78 | F10 (0.43) | STAT3F10CCR2BRAFHIF1A | |
| SCHEMBL1847418 | 0.77 | PRKAA2 (0.44) | SSTR5PRKAA2AKT1AKT2GRM2 | |
| Acetic Acid SCHEMBL2680690 | 0.76 | F10 (0.42) | SSTR5F10BRAFHIF1AEPAS1 | |
| SCHEMBL1844021 | 0.76 | WNK1 (0.43) | CCR2CHEK2UBE2MDCUN1D1 | |
| SCHEMBL2680691 | 0.75 | SSTR5 (0.36) | STAT3SSTR5CCR2PIK3CAPRKAA2 | |
| SCHEMBL1034197 | 0.75 | SCN9A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |