Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.41 |
| ▸ | AKT2 | P31751 | 5/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034167 | 0.90 | STAT3 (0.41) | AKT1AKT2PRKAA2GRM2CHEK2 | |
| SCHEMBL1031736 | 0.86 | STAT3 (0.41) | AKT1AKT2PRKAA2OPRM1OPRK1 | |
| SCHEMBL1847418 | 0.84 | PRKAA2 (0.44) | AKT1AKT2PRKAA2OPRM1OPRK1 | |
| SCHEMBL2681756 | 0.78 | F10 (0.44) | F10SSTR5 | |
| SCHEMBL1035444 | 0.77 | F10 (0.47) | F10 | |
| SCHEMBL1846809 | 0.77 | PRKAA2 (0.42) | PRKAA2OPRM1OPRK1GRM2KDM4A | |
| SCHEMBL1035168 | 0.74 | NPY5R (0.41) | KDM4AKDM4CKDM5BALOX5APFEN1 | |
| SCHEMBL1844021 | 0.73 | WNK1 (0.43) | OPRK1CHEK2 | |
| SCHEMBL17969664 | 0.68 | PRKAA2 (0.56) | PRKAA2 | |
| SCHEMBL12482191 | 0.68 | KDM4C (0.40) | AKT1AKT2SSTR5KDM4AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |