Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035168 | 0.86 | NPY5R (0.41) | HTR6MAPK14EGFRHTR1ASLC6A2 | |
| SCHEMBL1846196 | 0.82 | SLC6A2 (0.40) | HTR6MAPK14HTR1ASLC6A2SLC6A4 | |
| SCHEMBL1076389 | 0.78 | KDM4B (0.45) | MRGPRX4AURKAMAP2K4 | |
| SCHEMBL1034167 | 0.75 | STAT3 (0.41) | — | |
| SCHEMBL1031736 | 0.75 | STAT3 (0.41) | OPRK1 | |
| SCHEMBL29050696 | 0.74 | JAK2 (0.44) | — | |
| SCHEMBL26599370 | 0.73 | KDM5C (0.45) | EGFROPRK1 | |
| SCHEMBL30606793 | 0.73 | KDM5C (0.45) | EGFROPRK1 | |
| SCHEMBL3718581 | 0.71 | HDAC1 (0.56) | P2RY14AURKAOPRD1MAP2K4 | |
| SCHEMBL29932964 | 0.71 | HDAC1 (0.56) | P2RY14AURKAOPRD1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |