Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846809 | 0.88 | PRKAA2 (0.42) | PRKAA2GRM2KDM4CKDM4AKDM5A | |
| SCHEMBL1035443 | 0.84 | AKT1 (0.41) | PRKAA2GRM2KDM4CKDM4AKDM5A | |
| SCHEMBL1031736 | 0.81 | STAT3 (0.41) | PRKAA2OPRM1OPRK1AKT1AKT2 | |
| SCHEMBL12482191 | 0.79 | KDM4C (0.40) | KDM4CKDM4AKDM5AKDM5BMCHR1 | |
| SCHEMBL1034167 | 0.77 | STAT3 (0.41) | PRKAA2GRM2AKT1AKT2SSTR5 | |
| SCHEMBL1846196 | 0.77 | SLC6A2 (0.40) | KDM5BMAPK14 | |
| SCHEMBL1726547 | 0.76 | GSK3B (0.48) | MCHR1SSTR5CSNK1DCSNK1E | |
| SCHEMBL1844021 | 0.75 | WNK1 (0.43) | OPRK1 | |
| SCHEMBL1847421 | 0.75 | ACKR3 (0.49) | MCHR1 | |
| SCHEMBL1035168 | 0.70 | NPY5R (0.41) | KDM4CKDM4AKDM5BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |