Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559288 | 0.82 | MMP2 (0.56) | MMP2ITGA4ITGB7RAB9AHTT | |
| SCHEMBL6559285 | 0.82 | MMP2 (0.56) | MMP2ITGA4ITGB7RAB9AHTT | |
| Phenylmethanesulfonic Acid SCHEMBL10341839 | 0.81 | ITGA4 (0.49) | MMP2ITGA4ITGB7RAB9AHTT | |
| SCHEMBL6897867 | 0.79 | ITGA4 (0.46) | MMP2ITGA4ITGB7RAB9AALDH1A1 | |
| SCHEMBL10501021 | 0.79 | ITGA4 (0.46) | MMP2ITGA4ITGB7RAB9AALDH1A1 | |
| SCHEMBL10500994 | 0.79 | ITGA4 (0.46) | MMP2ITGA4ITGB7RAB9AALDH1A1 | |
| SCHEMBL10499174 | 0.77 | DPP8 (0.44) | MMP2ITGA4ITGB7RAB9AALDH1A1 | |
| SCHEMBL7737719 | 0.77 | RAB9A (0.55) | MMP2ITGA4ITGB7RAB9ASMN1; SMN2 | |
| SCHEMBL6141190 | 0.76 | SLC15A1 (0.45) | RAB9AALDH1A1POLBNPC1 | |
| SCHEMBL10668464 | 0.76 | SLC15A1 (0.45) | RAB9AALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156280-B1 | PROCESS FOR THE PREPARATION OF PEPTIDE INTERMEDIATES POOR IN RACEMATES, BELONGING TO GONADORELIN AND GONADORELIN ANALOGUES, THEIR SYNTHESIS AND INTERMEDIATES OBTAINED BY THIS PROCESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0156280-A2 | Process for the preparation of peptide intermediates poor in racemates, belonging to gonadorelin and gonadorelin analogues, their synthesis and intermediates obtained by this process | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-02 | — | — | EP | disclosed |