Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737719 | 0.88 | RAB9A (0.55) | ITGA4ITGB7MMP2RAB9AMC4R | |
| SCHEMBL6559285 | 0.87 | MMP2 (0.56) | ITGA4ITGB7MMP2RAB9AHTT | |
| SCHEMBL6559288 | 0.87 | MMP2 (0.56) | ITGA4ITGB7MMP2RAB9AHTT | |
| SCHEMBL10501021 | 0.82 | ITGA4 (0.46) | ITGA4ITGB7MMP2RAB9AMAPT | |
| SCHEMBL10500994 | 0.82 | ITGA4 (0.46) | ITGA4ITGB7MMP2RAB9AMAPT | |
| SCHEMBL6897867 | 0.82 | ITGA4 (0.46) | ITGA4ITGB7MMP2RAB9AMAPT | |
| SCHEMBL10341840 | 0.81 | MMP2 (0.42) | ITGA4ITGB7MMP2RAB9AHTT | |
| SCHEMBL16080193 | 0.80 | SLC7A5 (0.62) | SLC7A5MEN1KMT2A | |
| SCHEMBL121369 | 0.80 | SLC7A5 (0.62) | SLC7A5MEN1KMT2A | |
| SCHEMBL630209 | 0.80 | SLC7A5 (0.62) | SLC7A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156280-B1 | PROCESS FOR THE PREPARATION OF PEPTIDE INTERMEDIATES POOR IN RACEMATES, BELONGING TO GONADORELIN AND GONADORELIN ANALOGUES, THEIR SYNTHESIS AND INTERMEDIATES OBTAINED BY THIS PROCESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0156280-A2 | Process for the preparation of peptide intermediates poor in racemates, belonging to gonadorelin and gonadorelin analogues, their synthesis and intermediates obtained by this process | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-02 | — | — | EP | disclosed |