Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967915 | 0.89 | NOTUM (0.47) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10344654 | 0.89 | ALDH1A1 (0.46) | ELANEMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10594950 | 0.87 | PBRM1 (0.53) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10344503 | 0.87 | ELANE (0.47) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10596810 | 0.85 | ELANE (0.43) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17554151 | 0.82 | KDM4E (0.64) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11002682 | 0.80 | F7 (0.53) | ELANEMAPTNPC1RAB9APBRM1 | |
| SCHEMBL10344530 | 0.80 | MAPT (0.54) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL203587 | 0.78 | ELANE (0.61) | ELANEMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10595299 | 0.78 | ALDH1A1 (0.49) | ELANEMAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136646-B1 | PROCESS FOR THE PREPARATION OF 5-FLUOR-4H-3,1-BENZOXAZIN-4-ONES | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4562254-A | Preparation of 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-ones | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |