Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345280 | 0.84 | L3MBTL1 (0.41) | MAPK1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL847010 | 0.74 | LMNA (0.40) | ALDH1A1LMNAMAPT | |
| SCHEMBL1723277 | 0.69 | TDP1 (0.42) | MEN1KMT2AALDH1A1LMNAHTR1A | |
| SCHEMBL28914522 | 0.66 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1LMNACYP2C19 | |
| SCHEMBL10345211 | 0.63 | TSHR (0.50) | MEN1KMT2AALDH1A1LMNADRD2 | |
| SCHEMBL24780612 | 0.63 | KCNA3 (0.44) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL7253541 | 0.62 | TDP1 (0.44) | LMNAHTR1A | |
| SCHEMBL3227805 | 0.62 | MEN1 (0.41) | MEN1KMT2AALDH1A1HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10345286 | 0.62 | TSHR (0.49) | MEN1KMT2AALDH1A1LMNADRD2 | |
| SCHEMBL25599411 | 0.62 | NPC1 (0.42) | ALDH1A1DRD2TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152236-B1 | ARYLOXYMETHYLPYRROLIDINOLS AND PIPERIDINOLS HAVING ANTIDEPRESSANT, ANTIARHYTHMIC OR HYPOTENSIVE ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-04-18 | — | — | EP | claimed |