Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345161 | 0.84 | MAPK1 (0.36) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL10345698 | 0.69 | ALDH1A1 (0.46) | L3MBTL1GLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10345569 | 0.67 | CHRM2 (0.58) | L3MBTL1ALDH1A1HSD17B10KDM4ECHRM2 | |
| SCHEMBL10345149 | 0.65 | CHRM2 (0.53) | ALDH1A1KMT2AKDM4ECHRM2CHRM3 | |
| SCHEMBL10345634 | 0.64 | SIGMAR1 (0.45) | L3MBTL1GLAALDH1A1MAPTHCN4 | |
| Hydrochloric Acid SCHEMBL10345568 | 0.63 | SIGMAR1 (0.44) | L3MBTL1GLAALDH1A1MAPTHCN4 | |
| SCHEMBL10345611 | 0.63 | ACHE (0.44) | L3MBTL1GLAALDH1A1KDM4ECHRM2 | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.63 | ALDH1A1 (0.68) | L3MBTL1GLAALOX15ALDH1A1HPGD | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.63 | ALDH1A1 (0.68) | L3MBTL1GLAALOX15ALDH1A1HPGD | |
| Iodide SCHEMBL10345164 | 0.62 | ACHE (0.43) | L3MBTL1GLAALDH1A1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152236-B1 | ARYLOXYMETHYLPYRROLIDINOLS AND PIPERIDINOLS HAVING ANTIDEPRESSANT, ANTIARHYTHMIC OR HYPOTENSIVE ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-04-18 | — | — | EP | claimed |