Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 9/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345396 | 0.87 | ALOX5 (0.50) | ALOX5ESR1ESR2ADRA2AADORA3 | |
| SCHEMBL786818 | 0.86 | ESR1 (0.53) | ALOX5ESR1ESR2HSD17B10USP7 | |
| SCHEMBL3811351 | 0.84 | ESR1 (0.51) | ALOX5ESR1ESR2HSD17B10USP7 | |
| SCHEMBL27579602 | 0.83 | ALOX5 (0.50) | ALOX5ESR1ESR2ADRA2AADORA3 | |
| SCHEMBL4935679 | 0.83 | CA2 (0.50) | ALOX5KDM4EALDH1A1LMNAHIF1A | |
| SCHEMBL27485774 | 0.81 | ALOX5 (0.48) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| Bicarbonate SCHEMBL4566918 | 0.80 | PTPN1 (0.50) | ALOX5ESR1ESR2HSD17B10JAK2 | |
| SCHEMBL28252223 | 0.77 | HSD17B1 (0.45) | ESR1ESR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL465352 | 0.76 | TYR (0.58) | ALOX5ESR1ESR2ADRA2AADORA3 | |
| SCHEMBL28600186 | 0.76 | ALOX5 (0.55) | ALOX5ESR1ESR2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150455-B1 | COPOLYESTERCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4788275-A | DUCTILITY, IMPACT AND TENSILE STRENGTH, HEAT RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| US-4774315-A | POLYCARBONATEESTER COPOLYMERS FOR MOLDING | GENERAL ELECTRIC COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0272426-A2 | Copolyester carbonate composition | GENERAL ELECTRIC COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| EP-0272424-A2 | Copolyestercarbonate composition | GENERAL ELECTRIC COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| EP-0150455-A2 | Copolyestercarbonates | GENERAL ELECTRIC COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4506065-A | Copolyestercarbonates | GENERAL ELECTRIC COMPANY (US) | 1985-03-19 | — | — | US | disclosed |