Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340033 | 0.74 | MMP1 (0.42) | FDPSLMNA | |
| SCHEMBL13076967 | 0.69 | FAAH (0.32) | FDPS | |
| SCHEMBL22294124 | 0.66 | GAA (0.30) | — | |
| SCHEMBL15483615 | 0.66 | ALDH1A1 (0.32) | — | |
| SCHEMBL8672382 | 0.65 | LMNA (0.30) | LMNA | |
| Tetrahydrothiophene SCHEMBL7932493 | 0.61 | FDPS (0.40) | FDPS | |
| SCHEMBL15497004 | 0.61 | LMNA (0.31) | LMNA | |
| SCHEMBL12091667 | 0.61 | ALDH1A1 (0.34) | — | |
| SCHEMBL21579240 | 0.61 | ALDH1A1 (0.41) | — | |
| SCHEMBL19334588 | 0.59 | GAA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248854-B1 | NOVEL BISPHOSPHONIC DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1990-04-25 | — | — | EP | disclosed |
| US-4870063-A | Bisphosphonic acid derivatives, their production and use | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1989-09-26 | — | — | US | disclosed |