Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 18/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.50 |
| ▸ | GABRP | O00591 | 8/20 | 0.47 |
| ▸ | GABRD | O14764 | 8/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.47 |
| ▸ | GABRE | P78334 | 8/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526822 | 0.83 | GABRA2 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9525812 | 0.81 | GABRA2 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9458856 | 0.81 | GABRB3 (0.54) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10519709 | 0.78 | OXTR (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6976717 | 0.75 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10522675 | 0.75 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10698854 | 0.74 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8446536 | 0.74 | GABRB3 (0.45) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14996611 | 0.73 | GABRB3 (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL27772986 | 0.73 | GABRB3 (0.49) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200872-B1 | HERBICIDAL AND INSECTICIDAL AGENT BASED ON PYRAZOL DERIVATIVES | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| US-4746354-A | PRE- AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0224094-A2 | 1-Aryl-pyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0200872-A1 | Herbicidal and insecticidal agent based on pyrazol derivatives | BAYER AG (DE) | 1986-11-12 | — | — | EP | disclosed |