Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 12/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 19/20 | 0.43 |
| ▸ | GABRP | O00591 | 7/20 | 0.43 |
| ▸ | GABRD | O14764 | 7/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.43 |
| ▸ | GABRE | P78334 | 7/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526822 | 0.87 | GABRA2 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9458856 | 0.81 | GABRB3 (0.54) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10347986 | 0.81 | GABRB3 (0.50) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10437857 | 0.75 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9527645 | 0.74 | BACE1 (0.42) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10372959 | 0.73 | BACE1 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10400984 | 0.73 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10556834 | 0.73 | ACHE (0.41) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL20001726 | 0.73 | HIF1A (0.41) | — | |
| SCHEMBL10560567 | 0.72 | SMN1; SMN2 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| EP-0274642-A2 | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |
| EP-0257296-A1 | 4-Cyano(nitro)-5-oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0249033-A1 | 5-Oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4685956-A | 1-aryl-5-hydrazino-pyrazoles, compositions containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0212353-A2 | 1-Aryl-5-hydrazino-pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |