SCHEMBL10348124

SCHEMBL10348124

CCO[Si](CCCc1ccc(Oc2ccc(S(=O)(=O)N=[N+]=[N-])cc2)cc1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.33
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
FDFT1 P37268 2/20 0.32
BCL2L1 Q07817 2/20 0.32
BAK1 Q16611 2/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
PLAAT3 P53816 1/20 0.31
PLAAT5 Q96KN8 1/20 0.31
PLAAT2 Q9NWW9 1/20 0.31
PLAAT4 Q9UL19 1/20 0.31
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17076870 0.94 CA2 (0.36) CA2LMNAHTTSMN1; SMN2BCL2L1
SCHEMBL14798581 0.85 CA2 (0.38) CA2LMNAHTTSMN1; SMN2BCL2L1
SCHEMBL14798409 0.83 CA2 (0.35) CA2LMNAHTTSMN1; SMN2BCL2L1
SCHEMBL14798643 0.83 CA12 (0.40) CA2HTTSMN1; SMN2ALDH1A1CA9
SCHEMBL14798240 0.82 BCL2L1 (0.35) CA2LMNASMN1; SMN2BCL2L1BAK1
SCHEMBL14798576 0.77 CA2 (0.37) CA2LMNAHTTSMN1; SMN2BCL2L1
SCHEMBL579486 0.76 CA12 (0.46) CA2HTTALDH1A1CA9
SCHEMBL11595972 0.76 CA2 (0.56) CA2LMNAHTTSMN1; SMN2FDFT1
SCHEMBL14798246 0.76 CA2 (0.34) CA2LMNAHTTSMN1; SMN2BCL2L1
SCHEMBL14798250 0.75 CA2 (0.37) CA2LMNAHTTSMN1; SMN2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4552794-A Composition for tufted carpets containing azidosulfonyl silane crosslinker HERCULES INCORPORATED (US) 1985-11-12 US claimed
EP-0132962-B1 COMPOSITION FOR TUFTED CARPETS HERCULES INCORPORATED (US) 1990-06-06 EP disclosed
US-4552794-A Composition for tufted carpets containing azidosulfonyl silane crosslinker HERCULES INCORPORATED (US) 1985-11-12 US disclosed
US-4501846-A Composition for tufted carpets HERCULES INCORPORATED (US) 1985-02-26 US disclosed
EP-0132962-A2 Composition for tufted carpets HERCULES INCORPORATED (US) 1985-02-13 EP disclosed