Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 3/20 | 0.43 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768231 | 1.00 | LMNA (0.43) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL12768232 | 0.91 | TK1 (0.36) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL12697415 | 0.82 | TK1 (0.47) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL1032736 | 0.81 | TYMP (0.48) | — | |
| SCHEMBL2498542 | 0.80 | TK1 (0.42) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL24653132 | 0.80 | TK1 (0.53) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL2495634 | 0.79 | SLC5A2 (0.42) | LMNATK2BLMPMP22DNMT1 | |
| SCHEMBL12212659 | 0.79 | SLC5A2 (0.42) | LMNATK2BLMPMP22DNMT1 | |
| SCHEMBL12212880 | 0.78 | TK1 (0.44) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL10340460 | 0.77 | ADRB1 (0.51) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275538-B1 | NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY | TAGCYX BIOTECHNOLOGIES (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-8426569-B2 | DNA capable of being amplified by PCR with high selectivity and high efficiency | RIKEN (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20110053782-A1 | NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY | RIKEN (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2275538-A1 | NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY | Riken (JP) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053782-A1 | NOVEL DNA CAPABLE OF BEING AMPLIFIED BY PCR WITH HIGH SELECTIVITY AND HIGH EFFICIENCY | POLRMT, POLN, POLL | LMNA 1568/4885SMN1; SMN2 3594/4885ALOX12 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.