Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297607 | 0.89 | HSD11B1 (0.63) | HSD11B1PTGS2PTGS1CYP2D6MMP1 | |
| SCHEMBL2474755 | 0.83 | HTR2A (0.59) | HSD11B1CYP2D6MMP1MMP2MMP3 | |
| SCHEMBL9793431 | 0.82 | HTR6 (0.62) | KMT2AHTR6 | |
| SCHEMBL1585056 | 0.80 | HSD11B1 (0.59) | HSD11B1PTGS2CYP2D6MMP1MMP2 | |
| SCHEMBL29196139 | 0.80 | CA1 (0.50) | HSD11B1PTGS2PTGS1CYP2D6MMP1 | |
| SCHEMBL3444895 | 0.80 | HSD11B1 (0.65) | HSD11B1CYP2D6MMP1MMP2MMP3 | |
| SCHEMBL5086111 | 0.79 | HSD11B1 (0.51) | HSD11B1PTGS2PTGS1CYP2D6MMP1 | |
| SCHEMBL2947083 | 0.79 | ALDH1A1 (0.60) | HSD11B1PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL9797523 | 0.79 | HSD11B1 (0.57) | HSD11B1PTGS2PTGS1CYP2D6MMP1 | |
| SCHEMBL11980110 | 0.78 | HTR6 (0.70) | HSD11B1PTGS2PTGS1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022191049-A1 | POWDERY PRIMER COMPOSITION | ダイキン工業株式会社 | 2022-09-15 | — | — | WO | disclosed |
| EP-0264499-B1 | SULFONATED POLY(ARYL ETHER) RESINS AND INTERMEDIATE SILYL SULFONATE DERIVATIVES; METHODS OF MAKING THEM, AND MEMBRANES FORMED FROM THE RESINS | AMOCO CORPORATION (an Indiana corp.) (US) | 1990-08-01 | — | — | EP | disclosed |
| EP-0264499-A1 | Sulfonated poly(aryl ether) resins and intermediate silyl sulfonate derivatives; methods of making them, and membranes formed from the resins | AMOCO CORPORATION (an Indiana corp.) (US) | 1988-04-27 | — | — | EP | disclosed |