SCHEMBL5086111

SCHEMBL5086111

O=S(=O)(c1ccc(F)cc1)c1cccc(-c2ccccc2)c1S(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.51
MMP1 P03956 3/20 0.49
MMP2 P08253 3/20 0.49
MMP3 P08254 3/20 0.49
MMP9 P14780 3/20 0.49
MMP12 P39900 3/20 0.49
MMP13 P45452 3/20 0.49
MMP14 P50281 3/20 0.49
PTGS2 P35354 3/20 0.49
PTGS1 P23219 1/20 0.49
IKBKB O14920 1/20 0.48
CYP2D6 P10635 1/20 0.46
LMNA P02545 3/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 2/20 0.43
MITF O75030 1/20 0.43
CASP6 P55212 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793435 0.89 HTR6 (0.48) MMP1MMP2MMP3MMP9MMP12
SCHEMBL3297607 0.87 HSD11B1 (0.63) HSD11B1MMP1MMP2MMP3MMP9
SCHEMBL9462475 0.84 RAPGEF4 (0.41) HSD11B1MMP1MMP2MMP3MMP9
SCHEMBL2947086 0.84 PTGS2 (0.49) MMP1MMP2MMP3MMP9MMP12
SCHEMBL9462782 0.84 MMP1 (0.42) HSD11B1MMP1MMP2MMP3MMP9
SCHEMBL10355100 0.79 HSD11B1 (0.57) HSD11B1MMP1MMP2MMP3MMP9
SCHEMBL3420592 0.79 HSD11B1 (0.52) HSD11B1MMP1MMP2MMP3MMP9
SCHEMBL9480438 0.76 PGR (0.48) MMP2MMP3MMP9MMP12MMP13
SCHEMBL30901407 0.74 LMNA (0.49) HSD11B1PTGS2PTGS1LMNAALDH1A1
SCHEMBL7929318 0.74 MMP1 (0.57) MMP1MMP2MMP3MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191049-A1 POWDERY PRIMER COMPOSITION ダイキン工業株式会社 2022-09-15 WO disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed
EP-0264499-B1 SULFONATED POLY(ARYL ETHER) RESINS AND INTERMEDIATE SILYL SULFONATE DERIVATIVES; METHODS OF MAKING THEM, AND MEMBRANES FORMED FROM THE RESINS AMOCO CORPORATION (an Indiana corp.) (US) 1990-08-01 EP disclosed
EP-0264499-A1 Sulfonated poly(aryl ether) resins and intermediate silyl sulfonate derivatives; methods of making them, and membranes formed from the resins AMOCO CORPORATION (an Indiana corp.) (US) 1988-04-27 EP disclosed